1. To Setup Quotes:

• Enable Quotes in Quotes Setting and
• Add Manifest Line Description to Quote Line Item page layout

2. Create the Quote Process Builder (When_QLI_is_created_and_desc_manifest_is_empty)

• Navigate to Setup > Process Builder > Select New
  Process Name = When QLI is created and desc/manifest is empty
  API Name = When QLI is created and desc/manifest is empty
  Description = Pre-populate desc/manifest when it’s empty
  The process starts when = A Record Changes

•  Add the first criteria
  Criteria Name = lineDesc=empty?
  Criteria for executing Actions = Conditions are met
  Set Conditions = Field – [QuoteLineItem].Description, Operator – Is Null, Type – Boolean, Value – True
  Conditions = All of the conditions are met (AND)

• Add the Immediate Action
  Action Name = UpdateLineDesc
  Record = [QuoteLineItem] Criteria for Updating Records = No criteria – just update the records!
  Field = Line Item Description, Type = Field Reference, Value = [QuoteLineItem].Product2.Description

• Add a second criteria
  Criteria Name = manifest=empty?
  Criteria for executing Actions = Conditions are met
  Set Conditions = Field – [QuoteLineItem].Manifest_Line_Description__c, Operator – Is Null, Type – Boolean, Value – True
  Conditions = All of the conditions are met (AND)

• Add the Immediate Action
  Action Name = UpdateLineManifest
  Record = [QuoteLineItem] Criteria for Updating Records = No criteria – just update the records!
  Field = Manifest Item Description, Type = Field Reference, Value = [QuoteLineItem].Product2.Event_Manifest_Description__2

Example of finished process builder below: